Omair Anwar Mohiuddin

Name

Omair Anwar Mohiuddin

Designation

Associate Professor and Deputy Director

Email

omair.anwar@duhs.edu.pk

Office

Dow Research Institute of Biotechnology and Biomedical Sciences, 2nd Floor, Dow Research and Diagnostic Complex, Ojha Campus, DUHS

Qualifications

B-Pharm, MSc Medical Biotechnology (UK),
PhD Biomedical Sciences (US Fulbright Fellow)

Research

  1. ) H. Tauseef, K. Ahmed, F. Chaudhary, A. Salim, O. A. Mohiuddin. The Impact of Decellularization Method on the Cytocompatibility and Wound Healing Capability of Human Amniotic Membrane. Advanced Biology (2025).
  2. ) S. Hussain, F. Jameel, A. Arif, I. Khan, O. A. Mohiuddin, A. Salim, and Mujeeb-ur Rehman. Enhanced Wound Healing Effects of Nanoscale Lipid-Diclofenac Conjugates. Journal of Drug Delivery Science and Technology, 101: 106223 (2024).
  3. ) K. Ahmed, H. Tauseef, J. Ainuddin, M. Zafar, I. Khan, A. Salim, M.R. Mirza, O.A. Mohiuddin. Assessment of the proteome profile of decellularized human amniotic membrane and its biocompatibility with umbilical cord-derived mesenchymal stem cells. Journal of Biomedical Materials Research part A, 112(7), 1041-1056 (2024).
  4. ) F. Ramzan, S. Khalid, S. Ekram, A. Salim, T. Frazier, S. Begum, O. A. Mohiuddin, I. Khan. 3D bioscaffold support osteogenic differentiation of mesenchymal stem cells. Cell Biology International, 48(5), 594-609 (2024).
  5. ) H. Tauseef, K. Ahmed, O.A. Mohiuddin. Preparation of Decellularized Amniotic Membrane and Adipose-Derived Stem Cell Seeding. Adipose Derived Stem Cells: Methods and Protocols, 209-220 (2024).
  6. ) K. Ahmed, H. Tauseef, O.A. Mohiuddin. Combination of Adipose Stem Cells and Decellularized Adipose Tissue Hydrogel for Osteogenic Applications. Adipose Derived Stem Cells: Methods and Protocols, 195-207 (2024).
  7. ) J.A. Belgodere, H.R. Lassiter, J.T. Robinson, K.M. Hamel, E.L. Rogers, O. A. Mohiuddin, … and C.G. Sanchez, C. G. Biomechanical and Biological Characterization of XGel, a Human‐Derived Hydrogel for Stem Cell Expansion and Tissue Engineering. Advanced Biology, 7(8), 2200332 (2023).
  8. ) O. A. Mohiuddin, I. Khan, and A. Salim. Minocycline pre-treatment up-regulates antioxidant enzymes and enhances the regenerative potential of MSCs in rat myocardial infarction model. The Journal of the Pakistan Medical Association 73.2: S3-S8 (2023).
  9. ) F. Ramzan, S. Ekram, T. Frazier, A. Salim, O. A. Mohiuddin, and I. Khan. Decellularized Human Umbilical Tissue-Derived Hydrogels Promote Proliferation and Chondrogenic Differentiation of Mesenchymal Stem Cells. Bioengineering, 9(6), 239 (2022).
  10. ) F. Munmun, O. A. Mohiuddin, V.T. Hoang, M.E. Burow, B.A. Bunnell, V.M. Sola, A.R. Carpentieri, and P.A. Witt‐Enderby. The role of MEK1/2 and MEK5 in melatonin‐mediated actions on osteoblastogenesis, osteoclastogenesis, bone microarchitecture, biomechanics and bone formation. Journal of Pineal Research, 73(2), e12814 (2022).
  11. ) G. Rahman, T. Frazier, J.M. Gimble, and O. A. Mohiuddin. The Emerging Use of ASC/Scaffold Composites for the Regeneration of Osteochondral Defects. Frontiers in Bioengineering and Biotechnology, 10, 893992 (2022).
  12. ) M.A.A. Harrison, A. Al-Ghadban, B.T. O’Donnell, O. A. Mohiuddin, R.M. Wise, B.N. Sullivan, B.A. Bunnell. Establishing the Adipose Stem Cell Identity: Characterization Assays and Functional Properties. Scientific Principles of Adipose Stem Cell, 23-56 (2022).
  13. ) T. Frazier, K. Hamel, X. Wu, E. Rogers, H. Lassiter, J. Robinson, O. A. Mohiuddin, M. Henderson, and J.M. Gimble. Adipose-derived cells: building blocks of three-dimensional microphysiological systems. Biomaterials Translational, 2(4), 301 (2021).
  14. ) T. Frazier, C. Williams, M. Henderson, T. Duplessis, E. Rogers, X. Wu, K. Hamel, E.C. Martin, O. A. Mohiuddin, S. Shaik, R. Devireddy, B. Rowan, D. Hayes, J.M. Gimble. Breast Cancer Reconstruction: Design Criteria for a Humanized Microphysiological System. Tissue Engineering Part A, 27(7-8), 479-488 (2021).
  15. ) M.A. Harrison, R.M. Wise, B.P. Benjamin, E.M. Hochreiner, O. A. Mohiuddin, B.A. Bunnell. Adipose-Derived Stem Cells from Obese Donors Polarize Macrophages and Microglia toward a Pro-Inflammatory Phenotype. Cells, 10(1) (2020).
  16. ) O. A. Mohiuddin, J.M. Motherwell, E. Rogers, M.R. Bratton, Q. Zhang, G. Wang, D.J. Hayes, J.M. Gimble. Characterization and proteomic analysis of decellularized adipose tissue hydrogels derived from lean and obese human donors. Advanced Biosystems, 4(10) (2020).
  17. ) T. Frazier, A. Alarcon, X. Wu, O. A. Mohiuddin, J. Motherwell, A. Carlsson, R.J. Christy, J.V. Edwards, R.T. Mackin, N. Prevost, E. Gloster, Q. Zhang, G. Wang, D. Hayes, J.M. Gimble. Clinical Translational Potential for Adipose, Blood-Derived Biologicals, and Cellulose Materials: Cells, Exosomes, and Hydrogels. Biomolecules, 10(10) (2020).
  18. ) B.T. O’Donnell, C.J. Ives, O. A. Mohiuddin, B.A. Bunnell. Beyond the Present Constraints That Prevent a Wide Spread of Tissue Engineering and Regenerative Medicine Approaches. Frontiers in Bioengineering and Biotechnology, 7 (2019).
  19. ) O. A. Mohiuddin, B.T. O’Donnell, J.N. Poche, R. Iftikhar, R.M. Wise, J.M. Motherwell, B. Campbell, S.D. Savkovic, B.A. Bunnell, D.J. Hayes, J.M. Gimble. Human Adipose-Derived Hydrogel Characterization Based on In Vitro ASC Biocompatibility and Differentiation. Stem Cells International, 2019(1), 9276398 (2019).
  20. ) O. A. Mohiuddin, B. Campbell, J.N. Poche, M. Ma, E. Rogers, D. Gaupp, M.A.A. Harrison, B.A. Bunnell, D.J. Hayes, J.M. Gimble. Decellularized Adipose Tissue Hydrogel Promotes Bone Regeneration in Critical-Sized Mouse Femoral Defect Model. Frontiers in Bioengineering and Biotechnology, 7 (2019).
  21. ) M. Cowper, T. Frazier, X. Wu, L. Curley, M.H. Ma, O. A. Mohiuddin, M. Dietrich, M. McCarthy, J. Bukowska, J.M. Gimble. Human Platelet Lysate as a Functional Substitute for Fetal Bovine Serum in the Culture of Human Adipose Derived Stromal/Stem Cells. Cells, 8(7) (2019).
  22. ) O. A. Mohiuddin, B. Campbell, J.N. Poche, C. Thomas-Porch, D.A. Hayes, B.A. Bunnell, J.M. Gimble. Decellularized Adipose Tissue: Biochemical Composition, in vivo Analysis and Potential Clinical Applications. Advances in Experimental Medicine and Biology, 6 (2019).
  23. ) M. Fahima, P. Witt-Enderby, O. A. Mohiuddin, B.A. Bunnell, V. Hoang, M Burow. Role of MEK1/2 and MEK5 in melatonin-mediated osteoblastogenesis and osteoclastogenesis and bone formation in vitro and in a Balb (c) calvarial defect model. Journal of Bone Mineral Research, 34 (1) pp. 212-213 (2019).
  24. ) O. A. Mohiuddin, C. Biggs. Evaluation of the effect of natural peptide ‘Urocortin’on corticotrophin releasing factor (CRF) receptor expression in ND7/23 cells. Brazilian Journal of Pharmaceutical Sciences, 51(1) (2015).
  25. ) F. Owais, S. Anwar, S. Muhammad, S. Ishtiaque, O. A. Mohiuddin. Analgesic, Anti-inflammatory and neuropharmacological effects of Atropa belladonna. Pakistan journal of pharmaceutical Sciences, 27(6) (2014).
  26. ) M.I. Shaikh, M.A. Ghoto, A. Dayo, N. Jahan, O. A. Mohiuddin. Comparative effects of vitamin E and its combination with vitamin C on endothelial function in diabetic hypertensive patients. World Journal of Pharmaceutical Research, 3(4) (2014).
  27. ) T. Ali, O. A. Mohiuddin. In vitro interaction study of cefixime with diclofenac sodium, flurbiprofen, mefenamic acid and tiaprofenic acid. Journal of Chemical and Pharmaceutical Research, 4(6) (2012).
  28. ) H.M. Arshad, O. A. Mohiuddin, M.B. Azmi. Comparative in vitro antibacterial analysis of different brands of cefixime against clinical isolates of Staphylococcus aureus and Escherichia coli. Journal of Applied Pharmaceutical Science, 2(1) (2012).
  29. ) M. Ahmad, O. A. Mohiuddin, E. Mehjabeen, M. Anwar, S. Habib, S. Alam, I. Baig. Evaluation of spasmolytic and analgesic activity of ethanolic extract of Chenopodium album Linn and its fractions. Journal of Medicinal Plants Research, 6(31) (2012).
  30. ) M. Anwar, N.J. Mehjabeen, O. A. Mohiuddin, M. Qureshi. Phytopharmacological assessment of medicinal properties of Psoralea corylifolia. African Journal of Pharmacy and Pharmacology, 5(23) (2011).